4-aminobutyric acid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0508	γ-Aminobutyric acid	Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid	GABA Receptor , Endogenous Metabolite
	γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.		GABA Receptor , Endogenous Metabolite
T36415	N-Nitroso-N-methyl-4-Aminobutyric Acid
	N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces ...
T8630	Baclofen hydrochloride	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...		GABA Receptor
T4728	4-Acetamidobutanoic acid	N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID	GABA Receptor , Endogenous Metabolite , Antibacterial
	4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamid...		GABA Receptor , Endogenous Metabolite , Antibacterial
T11684	Isoguvacine hydrochloride	1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride	GABA Receptor
	Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2...		GABA Receptor
T8639	Phenibut (hydrochloride)	3-Amino-4-phenylbutyric acid hydrochloride	GABA Receptor
	Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor...		GABA Receptor
T2S1814	P-Hydroxybenzaldehyde	4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde	Transaminase , GABA Receptor , Endogenous Metabolite
	1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic...		Transaminase , GABA Receptor , Endogenous Metabolite
T14983	Clomethiazole	Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE	P450 , GABA Receptor
	Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C...		P450 , GABA Receptor
T4363	CGP52432	CGP 52432	GABA Receptor
	CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).		GABA Receptor
T0710	L-Cycloserine	Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone	HIV Protease , GABA Receptor
	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...		HIV Protease , GABA Receptor
T11307	Fluxametamide		GABA Receptor
	Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225...		GABA Receptor
T70114	Paclitaxel Ceribate
	Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
T0128	Vigabatrin	Sabril,Vigabatrine	GABA Receptor , ABC
	Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of γ-aminobutyric acid.		GABA Receptor , ABC
T22364	Methyl 4-aminobutyrate HCl	Methyl 4-aminobutyrate hydrochloride,GABA methyl ester	Others
	Methyl 4-aminobutyrate HCl (GABA methyl ester) is a methyl ester compound derived from the condensation of aminobutyric acid and methanol.		Others
T12492	Pivagabine	CXB-722	GABA Receptor
	Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor...		GABA Receptor
T40659	γ-Acetylenic GABA	4-Aminohex-5-ynoic acid,γ-Acetylenic GABA
	γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase. This compound effectively raises the concentration of γ-Aminobutyric acid (GABA) in the brain of rats.
T28901	T-2007	5,5-Diphenylbarbituric acid,DPB
	T-2007 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist and gamma-aminobutyric acid (GABA) receptor agonist. T2007 and its analogs upregulates CYP3A4 and MDR1. T-2007 depressed both t...
T71911	CGP-11130 HCl
	4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB r...
T65396	Piperazine 2HCl
	Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspecte...